Associate Scientist - Upstream Cell Culture

Job Description Summary Associate Scientist - Upstream Cell Culture #LI-Onsite Location: Durham, USA This role is based inDurham,USA.Novartis is unable to offer relocation support for this role. Please only apply if this location is accessibleforyou. The Technical Research & Development (TRD) Department drives the advancement of the Adeno‑associated virus (AAV) and Lentiviral vector (LVV) production platform across multiple development sites and manages the development, scale‑up, scale‑down, transfer, optimization, and characterization of processes for the clinical manufacturing of Novartis cell gene therapy products. Major Accountabilities Designs and executes gene therapy upstream process development studies. Supports early development study projects and late-stage process characterization and scaling up studies. Analyses and interprets experimental data from process studies with strong statistical mindset. Conducts laboratory studies to enhance AAV and LVV manufacturing technologies, capabilities, and processes (such as media development, bioreactor fed‑batch and perfusion process development, optimization and scale‑up). Perform experiments at different scales to support pre‑clinical, clinical and commercial programs. Assists the evaluation and introduction of new technologies. Authors technical reports and presents results of development studies both internally and externally. Collaborates with cross‑functional groups to coordinate studies. Other related duties as assigned. Essential Requirements Experience with bioreactor operation including ambr (15 & 250), bench‑top bioreactor, pilot‑scale bioreactor. Proficient in statistical analysis principles and software. Working knowledge and experience with Design of Experiment (DoE). Ability to analyze data to make data‑driven decisions and further progress development strategies. Knowledge of viral gene therapy and previous experience with AAV process development is preferred. Excellent team player with good communication skills. Compensation Summary The salary for this position is expected to range between $73,500.00 - $136,500.00 USD. The final salary offered is determined based on relevant skills and experience, and will be reviewed periodically. Novartis may change the published salary range based on company and market factors. Your compensation will include a performance‑based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards. Benefits US‑based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time‑off package including vacation, personal days, holidays and other leaves. Skills Desired Materials Science, Process Simulation EEO Statement The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. Accessibility and reasonable accommodations The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e‑mail to or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message. #J-18808-Ljbffr