About the role

The Ishizuka Lab (Yale School of Medicine) is recruiting a wet lab Post-graduate Research Associate to help build next-generation CRISPR-based tools that detect and reprogram inflammatory states and to validate novel cancer immunotherapy drug targets. The candidate will work at the intersection of immunology, synthetic biology, and cancer immunotherapy.

We are seeking, reliable, self-motivated and ambitious candidates who will be trusted to build reproducible analyses, produce interpretable results and communicate clearly with experimental and computational team members. Co-authorship is supported.

Commitment: We strongly prefer candidates who can commit to two consecutive one-year renewable terms (2 years total)

What you’ll do

·      Build CRISPR-based tools using molecular biology and cellular assays and validate them in vitro and in vivo

·      Develop and optimize mammalian cell-based assays

·      Design rigorous experiments with strong controls, reproducibility, and records

·      Collaborate closely with the team and communicate progress clearly in meetings; propose next experiments and new research directions

·      Develop publication-quality figures

·      Contribute to shared lab operations that keep research moving (ordering, inventory, sample tracking, protocol updates)

You might be a fit if you’re:

·      Self-motivated to build new tools/approaches and identify future therapies to help cancer patients

·      Rigorous, reliable and organized

·      Comfortable with both mentored and (with proper preparation) self-directed work

·      Experienced with mammalian cell culture, molecular cloning

• A clear communicator skilled in the visual display of data

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Preferred (not required)

·      Prior experience with CRISPR systems, reporter assays, pooled libraries, screening/selection concepts, or assay development

·      In vivo murine experience

·      Flow cytometry experience

·      Evidence of ownership (independent research project, thesis, etc)




Education

Bachelor’s or Master’s degree in immunology, biology, bioengineering or a related field.




How to apply

Email CV + brief cover letter + 3 references to




Optional but helpful: include a link to a poster, figure, or short write-up that shows how you think and document work.