Sr Associate Scientist – Purification Process Development

Foster City (Onsite – 5 days/week)

1-Year Contract

Position Summary

We are seeking a highly motivated Sr Associate Scientist to support downstream purification process development for biologics during pivotal and commercial development stages.

This is a hands-on laboratory-based role focused on bench-scale purification development, process characterization, and experimental execution in a fast-paced GMP-aligned environment.

The ideal candidate will have strong technical expertise in chromatography, filtration, and UF/DF operations, along with the ability to independently execute, troubleshoot, and optimize purification processes.

Core Responsibilities (Simplified)

Purification Development

• Execute bench-scale downstream purification (chromatography, filtration, UF/DF)
• Support process characterization, robustness, resin/membrane lifetime studies
• Generate and interpret experimental data under data integrity standards

Lab & Technical Execution

• Troubleshoot AKTA-based purification systems and workflows
• Improve reproducibility and process robustness
• Maintain lab readiness, instruments, and documentation (ELN, protocols, reports)

Cross-functional Support

• Collaborate with upstream/downstream teams
• Support implementation of new purification technologies

Must-Have Skills (Screening Critical)

Look for candidates with:

• MS + 4 yrs OR BS + 6 yrs relevant biotech/pharma experience
• Strong hands-on downstream purification experience
• Chromatography (Protein A, IEX, HIC, SEC ideally)
• Filtration + UF/DF (tangential flow filtration/TFF)
• Experience executing lab-scale purification experiments independently
• Strong data analysis + ELN documentation discipline

Nice-to-Have

• AKTA system experience
• UNICORN software proficiency
• Experience in process characterization / late-stage development
• Resin/membrane lifetime or robustness studies
• Exposure to commercial/clinical biologics development