Research Associate/ Senior Research Associate

Location: Durham, North Carolina 27713

Position type: Full Time

About TCRCure Biopharma Corp.

TCRCure is a clinical-stage biotechnology startup that brings novel TCR-T and CAR-T cell therapies to patients around the world. We focus on treating solid tumors with personalized cancer immunotherapies. Over the past years, we have developed 9 pipelines, built 3 platforms and launched 4 T cell therapies. Our team of scientists and engineers leverage their expertise in molecular engineering, TCR repertoire analysis, cancer immunology, and cell and gene therapy to advance our growing pipeline of next-generation therapies.

Job Description:

Our research team in RTP is seeking a highly motivated individual to perform hands-on laboratory work. The role will have rapidly evolving priorities and ever-changing workloads, so adaptability is a must. We value teamwork and collaboration, and effectively working with scientists and other associates in the group to help our product development succeed is expected. Responsibilities include but are not limited to: developing strategies for novel TCR-/CAR-T cell therapies; planning, and executing in vitro functional assays with human and mouse T cells; working independently and cross-functionally with the in vivo development team to validate the in vivo efficacy of our novel products; performing molecular biology experiments such as PCR, cloning, DNA/RNA extraction, and bacterial transformation etc. The candidate will prepare technical reports and presentations to illustrate and explain experiments, data, and conclusions.

Position Requirements:

- B.S. or M.S. (M.S. preferred) in Biological Sciences or a related scientific discipline,

·       Research Associate: 1 year minimum experience, industry experience preferred

·       Senior Research Associate: 3 years minimum experience, industry experience preferred; highly matched with the job requirements

- Hands-on experience with mammalian cell culture, T cell and other primary leukocyte culture, cell transfection, retro-/lenti-virus transduction; previous experience with CAR-T or immunotherapy is preferred

- Experience with ELISA and flow cytometry techniques. Experience with multiparametric flow cytometry is strongly preferred

- Experience with animal handling, sampling, and dosing is desired

- Working knowledge and broad understanding of immunology and adoptive cell therapy is required

- Working knowledge of molecular biology and cloning is required

- Proficiency with standard software and statistical analysis (e.g., Microsoft Office, Graph Pad Prism), FlowJo experience is strongly preferred

- Strong record-keeping skills; highly organized and detail-oriented

- Basic understanding of GLP, GDP and GMP requirements

- Excellent communication and interpersonal skills for working closely with a diverse array of team members

-Comfortable and efficient in a fast-paced, dynamic, and growing environment

To Apply:

TCRCure Biopharma provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, disability, genetic information, marital status, amnesty, or status as a covered veteran in accordance with applicable federal, state, and local laws. TCRCure Biopharma complies with applicable state and local laws governing non-discrimination in employment in every location in which the company has facilities. This policy applies to all terms and conditions of employment, including, but not limited to, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation, and training.

If you are interested in applying for this opportunity, please submit your resume and cover letter. All submissions will be evaluated, and interviews will be conducted for those applicants who most strongly fit our needs. If you are not contacted for an interview, your resume will remain on file and active for available positions for a period of one year.