Senior Associate Scientist (HPLC) Apply
We are hiring a Senior Associate Scientist to support analytical testing and characterization of polysaccharide-based drug candidates. This individual will execute and optimize a variety of biochemical and chromatographic assays, contribute to method development initiatives, and ensure high-quality data generation in support of research and development programs. This role requires strong hands-on experience in HPLC-based techniques, biochemical assays, and analytical software platforms, along with a commitment to data integrity, documentation excellence, and cross-functional collaboration.ResponsibilitiesPerform in-house assays for polysaccharide manufacturing, including in-process testing, process development and process characterization study sample analysis, including: HPLC-based assays (e.g., HPLC-RI, HPAEC-PAD, etc.), Spectrophotometric-based assays (e.g., UV/Vis, Lowry, PicoGreen, Anthrone, etc.), Enzyme- and/or Immuno assays (e.g., ELISA, MSD platforms), Nephelometry (e.g. Turbidity analysis), Metabolite Analysis (e.g. sugars), LC-MS-based assay. Prepare samples, reagents, standards, and controls according to established protocols.Troubleshoot instrumentation and assay performance issues to ensure reliable data output.Assist in developing, qualifying, and optimizing analytical methods for sample preparation, testing, and characterization.Support method transfer, robustness evaluation, and documentation updates.Proactively recommend improvements to increase assay sensitivity, reproducibility, and throughput.Utilize data analysis software platforms such as Empower and Chromeleon for HPLC data acquisition and analysis, and SoftMax Pro for MSD and spectrophotometric assay data analysis.Analyze, interpret, and summarize experimental data clearly and concisely.Prepare technical summaries and present findings to cross-functional teams (e.g., R&D, CMC, Quality).Maintain meticulous laboratory notebooks and electronic records in compliance with internal SOPs and laboratory standards.Ensure data integrity and adherence to applicable regulatory guidelines (e.g., GLP/GMP where applicable).Participate in audits, documentation reviews, and quality initiatives as needed.Collaborate effectively with scientists across disciplines to support program milestones.Demonstrate eagerness to learn new analytical techniques and scientific concepts.Integrate best laboratory practices and contribute to a culture of operational excellence.QualificationsMSc in Chemistry/Biochemistry, Biotechnology, or similar degree with a minimum of 3 years of relevant industry experience, or BSc with a minimum of 5 years of relevant industry experience.Hands-on experience with HPLC systems and carbohydrate or polysaccharide analysis.Experience with HPAEC-PAD is preferred.Experience with LC-MS/MS is a plus.Experience with Empower and/or Chromeleon software.Familiarity with biochemical assays (ELISA, colorimetric, fluorescence-based assays).Experience working with polysaccharides, biologics, or complex drug substances.Experience in in-process monitoring and testing for process-related impurities.Knowledge of regulatory expectations for analytical documentation.Experience supporting CMC, process development, or analytical development programs.Salary$116,480-$128,960Why Choose R&D Partners?As an employee, you have access to a comprehensive benefits package including:Medical insurance – PPO, HMO & HSADental & Vision insurance401k planEmployee Assistance ProgramLong-term disabilityWeekly payrollExpense reimbursementOnline timecard approvalR&D Partners is a global functional service provider and strategic staffing resource specializing in scientific, clinical research & engineering. We provide job opportunities within major pharmaceutical, biopharmaceutical, biotechnology, and medical device companies.R&D Partners is an equal-opportunity employer.

