Scientist II – HPLC Method Development

Position Title: Scientist II - Analytical Work Location: San Diego, CA, 92111 (No relocations) Assignment Duration: 6 month contract, with extensions possible Work Arrangement: OnsitePosition Summary:The Organization is searching for an outstanding Scientist II to join the Gene Medicines team in San Diego, CA. This position offers an exciting opportunity to work with new non-viral nucleic acid delivery tools for in vivo genome editing and gene therapy applications. This person will be engaged in the analysis of novel lipid nanoparticle-based pharmaceuticals.Key Responsibilities:• Work at the direction of Analytical scientists to analyze lipid nanoparticles (LNPs) encapsulating nucleic acids and LNP components using HPLC and Biolayer Interferometry (BLI)• Develop methods to characterize LNPs and LNP components• Establish relationships between physiochemical characteristics of experimental nanoparticle formulations and their efficacy and safety• Maintain detailed records of analytical data• Interface directly with other functional teams• Share responsibility for basic lab management activities (supply ordering, instrument calibration, maintaining schedules)Qualification & Experience:• Master’s or Bachelor’s degree with 5+ years experience in pharmaceutical sciences, bioengineering, chemical engineering, chemistry, or related scientific discipline (an equivalent combination of education and experience may be considered).• Experience developing methods in gradient-elution HPLC modalities such as RP, IPRP, or AEX is required• Experience with BLI or Surface Plasmon Resonance (SPR) is highly desirable• Experience with LCMS is desirable• Excellent attention to detail and ability to produce consistent results and effectively communicate them to the team• Ability to be a team player, multitask and work on multiple projects at once, and excel in a collaborative work environment.• Proficiency at MS Excel is required; prior experience with advanced analytical software (Prism, JMP) is desirable• Excellent oral and written communication skillsApplicant Notices & DisclaimersFor information on benefits, equal opportunity employment, and location-specific applicant notices, click hereAt SPECTRAFORCE, we are committed to maintaining a workplace that ensures fair compensation and wage transparency in adherence with all applicable state and local laws.